demyelination相关论文
Rg1 exerts protective effect in CPZ-induced demyelination mouse model via inhibiting CXCL10-mediated
Myelin damage and abnormal remyelination processes lead to central nervous system dysfunction.Glial activation-induced m......
Brief electrical nerve stimulation enhances intrinsic repair capacity of the focally demyelinated ce
Our lab has shown that brief electrical nerve stimulation (ES) has a dramatic impact on remyelination of lysophosphatidy......
Role of microtubule dynamics in Wallerian degeneration and nerve regeneration after peripheral nerve
Wallerian degeneration, the progressive disintegration of distal axons and myelin that occurs after peripheral nerve inj......
Modeling subcortical ischemic white matter injury in rrodents: unmet need for a breakthrough in tran
Subcortical ischemic white matter injury (SIWMI), pathological correlate of white matter hyperintensities or leukoaraios......
The obstacle to successful remyelination in demyelinating diseases,such as multiple sclerosis,mainly lies in the inabili......
Myt1L Promotes Differentiation of Oligodendrocyte Precursor Cells and is Necessary for Remyelination
The differentiation and maturation of oligodendrocyte precursor cells (OPCs) is essential for myelination and remyelinat......
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Objective Cathepsin C(dipeptidyl peptidase I,DPPI)is a lysosomal cysteine proteinase,which belongs to papain superfamily......
The aim of this study is to investigate the effect of Nlrp3 on the anxiety in demyelinated mice....
Chronic treatment with caffeine attenuates inflammatory brain injury in experimental autoimmune ence
Caffeine,arguably the most widely consumed psychoactive drugs,has been recently shown to protection neuronal injury in a......
Enhanced pain sensitivity with systemic ultrastructural changes of the nervous systems after local c
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Lacking of cystatin F gene aggravates cuprizone-induced demyelination caused by severe invasion of m
Demyelination coincides with numerous changes of gene expression in the central nervous system (CNS).Cystatin F (cys F),......
Lysolecithin-induced axonal demyelination in the dorsal funiculus of the mouse cervical spinal segme
Here, we established an effective model and evaluation system for lysolecithin-induced demyelination in the dorsal funic......
This study was aimed to assess remyelination and axon regeneration of compounds using Hunter Biotechs zebrafish MS model......
Electroacupuncture promotes remyelination via the recruitment of microglia into corpus callosum clea
Multiple sclerosis (MS) is considered to be an autoimmune-mediated demyelinating disease of central nervous system (CNS)......
It has long been known that the brain governs the body functions with feedforward and feedback neural signals conducted ......
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目的探讨低频磁疗对双环己酮草酰二腙(CPZ)诱导的脱髓鞘模型小鼠胼胝体区髓鞘及炎性反应的影响。方法将36只6~8周龄雄性C57BL/6J小......
OBJECTIVE The proteasome inhibitor bortezomib(BTZ)is a first-line anti-multi⁃ple myeloma drug.BTZ-induced peripheral ne......
Peripheral conditioning lesion refers to the phenomenon that an initial peripheral nerve injury induces an intrinsic......
Cyclin dependent kinase 5 mediates oligodendrocyte development, myelination and myelin repair in rod
The major function of oligodendrocytes(OLs)is the formation of myelin sheaths in the CNS.Oligodendrocytes develop fr......
目的研究铜腙诱导的脱髓鞘小鼠是否对慢性不可预测应激诱导的抑郁样行为更加易感，以及其潜在神经病理学改变。方法C57BL/6小鼠随机......
Correlation between tibial nerve ultrastructural abnormalities and post-mercury poison-induced muscu
BACKGROUND: The pathways induced/activated by mercury poisoning that lead to muscle pain remain unclear. The present stu......
Effects of diethyldithiocarbamate on myelin basic protein expression in the rat lateral olfactory tr
BACKGROUND: Dithiocarbamates can cause demyelination of axons in the peripheral nervous system. Its derivate, diethyldit......
Spinal cord injuries (SCI) usually result in impairment of axonal conduction and sensorimotor function. There are no eff......
The calcium-binding protein Mtsl/S100A4 in normal,degenerating and demyelinated spinal cord of the a
目的:研究止常、退行性病变以及脱髓鞘小鼠脊髓内Mtsl/S100A4蛋白的表达模式,及其对胶质细胞反应的影响.方法:以野生型和Mtsl/S100......
目的 探讨12月龄APP/PS1转基因小鼠学习记忆能力下降与胼胝体脱髓鞘损伤之间的关系.方法 12只12月龄APP/PS1转基因小鼠为AD组,12只......
The calcium-binding protein Mtsl/S100A4 in normal,degenerating and demyelinated spinal cord of the a
目的:研究止常、退行性病变以及脱髓鞘小鼠脊髓内Mtsl/S100A4蛋白的表达模式,及其对胶质细胞反应的影响.方法:以野生型和Mtsl/S100......
Conditional Deletion of Foxgl Alleviates Demyelination and Facilitates Remyelination via the Wnt Sig
The massive loss of oligodendrocytes caused by various pathological factors is a basic feature of many demyelinating dis......
Dynamic glial response and crosstalk in demyelination- remyelination and neurodegeneration processes
Multiple sclerosis is an autoimmune disease in which the immune system attacks the myelin sheath in the central nervous ......
目的改进双环己铜草酰二腙(cuprizone,CPZ)诱导脱髓鞘小鼠模型的制备方法,为治疗脱髓鞘疾病提供更精准快速的动物模型。方法取60只......
多发性硬化症(MS)是一种可在中枢神经系统引起髓鞘缺失的炎症性疾病，对该病的研究因其标本难以获取而备受限制。建立相应的动物疾病......
格林-巴利综合征(GBS)又称急性炎性脱髓鞘性多发性神经病(AIDP)，是比较常见的神经系统疾病，是一种以周围神经广泛炎症性节段性脱髓鞘......
周围神经损伤(PNI)可导致轴突退变和脱髓鞘。脱髓鞘后施万细胞将去分化并形成Büngner带，进而为轴突再生及其再髓鞘化创造条件，所以......
To facilitate live imaging of demyelina-tion and remyelination, we have generated aXenopus laevis transgenic line,MBP-GF......
Quantification of Oligodendrocyte Progenitor Cells in Human and Cat Optic Nerve:Implications for End
促进来源于少突胶质祖细胞(OP)的少突胶质细胞髓鞘再生,提高内源性修复是改善多发性硬化运动障碍的重要方法之一,其重要前提是明确......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Demyelinating central nervous system lesions, following the use of tumor necrosis factor alpha antag
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Quantification of Oligodendrocyte Progenitor Cells in Human and Cat Optic Nerve:Implications for End
促进来源于少突胶质祖细胞(OP)的少突胶质细胞髓鞘再生,提高内源性修复是改善多发性硬化运动障碍的重要方法之一,其重要前提是明确......
目前认识到重症急性胰腺炎合并脑功能障碍存在脱髓鞘病理改变,检测脑脊液、血液髓鞘碱性蛋白以及头颅磁共振扫描有助于诊断脱髓鞘......
关于多发性硬化（multiple sclerosis，MS）斑块的病理以及MS患者灰白质的弥散性改变，目前已有相当多的深入研究报道。但对于脱髓鞘斑块周......
目的:分析临床药师参与典型疑难危重患者的诊治过程,总结药学监护中临床药师应具备的临床及药学思维,以便更好地服务临床工作。方......
癫痫是大脑神经元反复超同步异常放电引起的大脑功能障碍.国内外的研究发现,癫痫发作后存在胶质细胞增生、神经元变性、坏死及中枢......
原发性胆汁性肝硬化是一种慢性肝内胆汁淤积性疾病,易与类风湿性关节炎、干燥综合征、硬皮病等多种疾病并存,合并脊髓脱髓鞘者少见......
目的 :探讨临床工作中对脱髓鞘性脑炎一组疾病的诊断及治疗。方法 :收集 6 0例住院病人 ,就其临床特点、分型及疗效进行分析。结果......
目的探究丹参酮Ⅱa对实验性自身免疫性脑脊髓炎小鼠的病理影响。方法从泉州实验动物公司购买60只小鼠,健康C57BL/6雌性小鼠,8~13周......
